How Acclivum2.0 Is Made — Pharmaceutical Precision in Every Step

From high-purity ingredients to multi-layer protection and rigorous testing, every stage of Acclivum2.0’s production reflects uncompromising quality and scientific excellence.
Acclivum2.0 is produced under the highest pharmaceutical manufacturing standards, using advanced technology and robust quality systems to guarantee purity, stability, and safety. Each step of the process—from raw material selection to final packaging—is carefully monitored to meet or exceed global quality benchmarks.
1. Raw Material Reception
Only high-purity sodium bicarbonate is accepted for production. Every incoming batch undergoes strict quality control testing to confirm chemical composition, particle integrity, and purity before processing.
2. Pellet Production
The approved bicarbonate is processed into micropellets (Ø < 1.2 mm), ensuring uniform size, precise dosing, and controlled release properties. This advanced granulation process supports the stability and consistency of every batch produced.[/et_pb_text][/et_pb_column][/et_pb_row][et_pb_row column_structure="1_2,1_2" use_custom_gutter="on" gutter_width="2" make_equal="on" _builder_version="4.27.5" _module_preset="default" max_width="1221px" custom_margin="||||false|false" custom_padding="||||true|true" global_colors_info="{}"][et_pb_column type="1_2" _builder_version="4.27.4" _module_preset="default" background_color="#3f4547" custom_padding="30px|30px|30px|30px|true|true" border_radii="on|30px|30px|30px|30px" global_colors_info="{}"][et_pb_text _builder_version="4.27.5" _module_preset="default" text_font="Titillium Web|700|||||||" text_text_color="#FFFFFF" text_font_size="30pt" text_letter_spacing="1px" text_line_height="1.1em" custom_margin="21px||-2px||false|false" custom_margin_tablet="|19px||19px|false|true" custom_margin_phone="|19px||19px|false|true" custom_margin_last_edited="off|desktop" custom_padding="||4px|||" custom_padding_tablet="||4px|||" custom_padding_phone="||4px|||" custom_padding_last_edited="on|tablet" text_font_size_tablet="34pt" text_font_size_phone="6vw" text_font_size_last_edited="on|desktop" global_colors_info="{}"]3. Multiple Coatings & Protection Layers[/et_pb_text][et_pb_image src="https://acclivum.com/wp-content/uploads/2025/12/Alak-3-min-1.jpg" title_text="Alak-3-min" _builder_version="4.27.4" _module_preset="default" custom_margin="24px||||false|false" global_colors_info="{}"][/et_pb_image][et_pb_text _builder_version="4.27.5" _module_preset="default" text_font="Titillium Web||||||||" text_text_color="#FFFFFF" text_font_size="14pt" text_letter_spacing="1px" text_line_height="1.4em" custom_margin="||||false|false" custom_margin_tablet="|19px||19px|false|true" custom_margin_phone="|19px||19px|false|true" custom_margin_last_edited="off|desktop" custom_padding="18px||4px|||" text_font_size_tablet="12pt" text_font_size_phone="12pt" text_font_size_last_edited="on|desktop" global_colors_info="{}"]

At the heart of Acclivum2.0 is its multi-layer dual-membrane technology. Each pellet receives a sequence of specialized coatings designed to:

  • Protect the bicarbonate core from stomach acid, preventing premature reaction.
  • Enable precise release and activation in the small intestine (duodenum)—the body’s natural site of bicarbonate function.

This system ensures bioavailability, tolerance, and consistent performance across every dose.

4. Market Formulation & Packaging
After coating, Acclivum2.0 is incorporated into various market-ready product formats suited for nutritional or supplement applications. Final packaging is performed in controlled, contamination-free environments, maintaining full traceability and product integrity.
5. Quality Systems and Controls

Acclivum2.0 production follows comprehensive Good Manufacturing Practice (GMP) and HACCP protocols:

  • GMP compliance guarantees pharmaceutical-grade quality from start to finish.
  • HACCP principles ensure contamination-free and safe processing.
  • Independent testing and quality control are conducted at multiple stages—including by accredited university laboratories—to validate safety, consistency, and efficacy.
6. Certifications & Standards

Acclivum2.0 is backed by internationally recognized certifications that reflect its commitment to excellence:

  • ISO 9001 – Quality Management
  • ISO 14001 – Environmental Management
  • ISO 50001 – Energy Management

Every batch of Acclivum2.0 embodies science, precision, and reliability—delivering a new benchmark in nutritional innovation and manufacturing integrity.